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曹修岭
作者: 点击数: 时间:2024/03/06 08:36

  

 

个人简介

曹修岭,博士,副教授,硕士生导师。

研究方向

利用高通量表型组平台开展细胞衰老及抗衰老活性成分机理的研究。

工作和学习经历

2017.09-至今     浙江农林大学 林业与生物技术学院 专任教师

2015.08-2017.09    瑞典哥德堡大学 化学与分子生物学系 博士后

2009.09-2015.07    中国农业大学 生物学院 硕博连读

教学与课程

研究生:《高级生物化学》《生物学材料与研究方法》《植物细胞生物学技术与方法》

本科生:《衰老的秘密》《高级微生物研究法》

科研项目

1.国家自然科学基金青年项目, 32000387,酵母衰老过程中Yhb1生理性聚集对α-synucleinsynphilin-1细胞毒性的影响及其机制研究,   2021.01-2023.12, 24,主持

 

2.浙江省自然科学基金青年项目, LQ19C070001,   synphilin-1蛋白聚集体在酵母中与线粒体互作的原位结构及其对线粒体功能影响的分析,   2019.01-2021.12, 9,主持

 

3.国家自然科学基金青年项目, 31800163, JB6细胞壁的三维结构、组成成分及其在JB6适应碳酸盐胁迫中的作用分析,   2019.01-2021.12, 27,参与 

代表性论文

1Xuejiao Jin(co-first), Min   Zhou(co-first), Shuxin Chen, Danqi Li,Xiuling Cao*,   Beidong Liu*, Effects of pH alterations on stress- and   aging-induced protein phase separation,Cellular   and Molecular Life Sciences, 2022, 79(7):380

2Xiuling Cao(co-first)*, Tingting   An(co-first), Wenhao Fu, Jie Zhang, Huihui Zhao, Danqi Li, Xuejiao Jin*,   Beidong Liu*, Genome-wide identification of cellular pathways and   key genes that respond to sodium bicarbonate stress inSaccharomyces cerevisiae,Frontiers in Microbiology, 2022,   13:831973

3Wenhao Fu(co-first),Xiuling   Cao(co-first)*, Tingting An, Huihui Zhao, Jie Zhang,   Danqi Li, Xuejiao Jin*, Beidong Liu*, Genome-wide   identification of resistance genes and transcriptome regulation in yeast to   accommodate ammonium toxicity,BMC   Genomics, 2022, 23(1):514

4Xuejiao Jin(co-first), Huihui   Zhao(co-first), Min Zhou, Jie Zhang, Tingting An, Wenhao Fu, Danqi Li,Xiuling   Cao*, Beidong Liu*, Retromer complex and PI3K   complex II-related genes mediate the yeast (Saccharomyces   cerevisiae) sodium metabisulfite resistance response,Cells, 2021, 10(12):3512

5Xuejiao Jin,Xiuling Cao   (co-first), Shenkui Liu*, and Beidong Liu*, Functional roles of   Poly(ADP-Ribose) in stress granule formation and dynamics,Frontiers in Cell and Developmental Biology,   2021, 9: 671780.

6Xuejiao Jin, Jie Zhang (co-first),   Tingting An (co-first), Huihui Zhao, Wenhao Fu, Danqi Li, Shenkui Liu,Xiuling   Cao*, and Beidong Liu*, A genome-wide screen inSaccharomyces cerevisiaereveals a   critical role for oxidative phosphorylation in cellular tolerance to lithium   hexafluorophosphate,Cells,   2021, 10(4): 888.

7Xiuling Cao, Xuejiao Jin, and Beidong Liu*,   Genome-wide imaging-based phenomic screening using yeast (Saccharomyces cerevisiae) strain   collections,Methods in Molecular   Biology, 2021, 2196:85-95.

8Xiuling Cao, Xuejiao Jin (co-first), Beidong Liu*,   The involvement of stress granules in aging and aging associated diseases,Aging Cell, 2020, 00: e13136.

9Xiaoling Wang,Xiuling Cao   (co-first), Min Liu, Ruiqi Zhang, Xin Zhang, Zongyu Gao, Xiaofei   Zhao, Kai Xu, Dawei Li, Yongliang Zhang*, Hsc70-2 is required forBeet black scorch virusinfection   through interaction with replication and capsid proteins,Scientific Reports, 2018, 8(1):   4526.

10Junsheng Yang, Xinxin Hao,Xiuling   Cao, Beidong Liu*, Thomas Nyström*, Spatial sequestration and   detoxification of Huntingtin by the ribosome quality control complex.eLife, 2016, 5: e11792.

11Xiuling Cao, Xuejiao Jin, Xiaofeng Zhang, Ying Li,   Chunyan Wang, Xianbing Wang, Jian Hong, Xiaofeng Wang, Dawei Li, Yongliang   Zhang*, Morphogenesis of endoplasmic reticulum membrane-invaginated vesicles   duringBeet Black Scorch Virusinfection:   role of auxiliary replication protein and new implications of   three-dimensional architecture,Journal   of Virology, 2015, 89(12): 6184-6195.

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联系方式

通讯地址:浙江省杭州市临安区武肃街666号国家重点实验室大楼

编:311300

箱:cxiuling@zafu.edu.cn

 

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